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Terrence Higgins Trust Re-Launches Support Group For Gay Men With Hepatitis C And HIV, UK On Thursday 12 August, Terrence Higgins Trust (THT) will be running another six week course for gay men who are living with HIV and Hepatitis C. The group will meet each week from 6.30 - 9.30pm in central London. The course looks at living with both HIV and Hepatitis C, but the primary focus will be on Hepatitis... ANA598 Demonstrates SVR12 In 100% Of First Group Of HCV Patients Randomized To Stop All Treatment At Week 24 Anadys Pharmaceuticals, Inc. (Nasdaq: ANDS) announced that six of six patients (100%) in the ANA598 200 mg twice daily (bid) arm who were randomized to stop all treatment at Week 24 in an ongoing Phase II trial maintained undetectable levels of virus 12 weeks after stopping treatment, referred to as Sustained Virological Response 12, or SVR12... Pharmasset Initiates Phase 1b Multiple Ascending Dose Clinical Trial Of PSI-938 In Patients With Chronic Hepatitis C Pharmasset, Inc. (Nasdaq: VRUS) announced that safety and pharmacokinetic data from the PSI-352938 ("PSI-938") single ascending dose study support progression to a multiple ascending dose trial with PSI-938, which has initiated dosing. PSI-938 is a guanine nucleotide analog polymerase inhibitor for the treatment of chronic hepatitis C virus (HCV) infection... New Transplantation Criteria For Liver Cancer Patients Researchers at the University of California, San Francisco propose that treatments used on liver cancers beyond the established Milan criteria for liver transplantation may be appropriate for all patients with hepatocellular carcinoma (HCC) who are listed for transplantation... Novel Hepatitis C Treatments Gets A Leg Up From The Increasing Number Of Diagnosed Cases, Finds Frost & Sullivan The Singaporean government's emphasis on raising awareness on the benefit of frequent health check-ups have significantly raised the number of Hepatitis C Virus (HCV) diagnosed cases in the country, expanding the patient pool... Can-Fite Drug Candidate CF102 Significantly Decreased Viral Load Of HCV In 3 Patients With Liver Cancer Can-Fite BioPharma Ltd (TASE:CFBI), a biotechnology company traded on the Tel Aviv Stock Exchange reported that a significant decrease in HCV viral load was detected in 3 patients with liver cancer who are treated daily orally with CF102. The company is studying CF102 as a treatment for liver cancer (hepatocellular carcinoma, or HCC)... AIDS 2010: Strong Scientific Findings Point To Promise Ahead And Underscore The Need To Stay The Course The biennial meeting of the global AIDS community concluded with clear evidence of tangible progress in HIV research and programme scale up, yet facing an urgent need for increased resources, the protection of human rights, and broader use of scientifically sound prevention strategies... Hepatitis Virus Transmission Through Misuse Of Anesthesia Hepatitis B virus (HBV) and hepatitis C virus (HCV) can be transmitted during intravenous (IV) administration of anesthesia, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association (AGA) Institute. In this study, doctors found that anesthesia contamination - not endoscopy contamination - was the cause of infection... A Food-Related Method For The Diagnosis Of Hepatic Steatosis A multidisciplinary research team from the Instituto Biodonostia made up by digestologists, epidemiologists and researchers of the Experimental Unit evaluated the use of a method so far employed in the food industry to improve the diagnosis of hepatic steatosis. Fatty liver is one of the most frequent liver diseases and it is promoted by obesity and diabetes... HCV Therapy Compromised When Depression Overlooked In Patients With Hepatitis C Researchers from Denmark, Sweden, Norway and Finland (the NORDynamIC project group) have observed that depressive symptoms in patients with hepatitis C virus (HCV) infection are commonly overlooked in routine clinical interviews, and that treatment-induced depression compromises the outcome of HCV therapy. A second U.S... Drug For NASH Patients Fails To Improve Overall Liver Histology Compared To Placebo A study conducted by researchers at Johann Wolfgang Goethe University in Frankfurt, Germany found that high doses of ursodeoxycholic acid (UDCA), suggested by some studies to have a beneficial effect on nonalcoholic steatohepatitis (NASH), does not improve overall histology in these patients... Imminent Launch Of Small-molecule Antiviral Drugs Poised To Enhance Treatment Success Rates For Hepatitis C Patients, Finds Frost & Sullivan Efforts to raise disease awareness in the Philippines have increased the number of cases and patient pool available for hepatitis C treatment. Screening and detection efforts by the Red Cross as well as growing awareness in the Philippines have been largely responsible for the rise in the number of diagnosed cases... Administration's National HIV/AIDS Strategy Recognizes Need For Better Care Coordination For Individuals Co-Infected With Viral Hepatitis With millions of Americans living with HIV/AIDS, chronic viral hepatitis, or a combination of both, the National Viral Hepatitis Roundtable (NVHR) welcomes the Administration's recognition of the need for better care coordination and integration of services for these individuals and supports recommendations contained within the new National HIV/AIDS strategy released yesterday in Washington... Newly Discovered Hepatitis C-Related Virus Found In Bats Wildlife Trust, the global conservation health organization, announced the discovery of a previously unknown pathogen that may offer insight into the origins of the Hepatitis C virus. The virus, tentatively named GBV-D, is related to a group of GB viruses, previously only known to occur in monkeys and humans. Dr... In Detection Of Hepatic Toxicity, Perfusion CT May Be Used As A Noninvasive Tool Liver damage is common in patients with tumors following chemotherapy. Although early liver damage causes no symptoms and is reversible in most patients, it occasionally progresses to more severe liver impairment, which may be irreversible, it is thus necessary to demonstrate the presence and severity of drug-related parenchymal changes... Response Of Hepatocellular Carcinoma To Chemoembolization May Be Predicted By Functional MRI Early knowledge of hepatocellular carcinoma (HCC) response to transcatheter arterial chemoembolization (TACE) is crucial for determining treatment success, timing of repeat treatment, and patient prognosis. Currently, magnetic resonance imaging (MRI) is used 1-3 months after treatment to evaluate anatomical tumor response, based upon changes in tumor size and contrast-agent enhancement... Three Rivers Pharmaceuticals Announces FDA Approval Of Expanded Labeling Of INFERGEN(R) Three Rivers Pharmaceuticals, LLC, received expanded labeling from the U.S. Food and Drug Administration (FDA) to include daily use of INFERGEN (Consensus Interferon) in combination with ribavirin (RBV) for retreatment of chronic hepatitis C patients. The expanded labeling targets hepatitis C patients who need retreatment... FDA Approves Rapid Test For Antibodies To Hepatitis C Virus The U.S. Food and Drug Administration announced approval of the first rapid blood test for antibodies to the hepatitis C virus (HCV) for individuals 15 years and older. The OraQuick HCV Rapid Antibody Test is used to test individuals who are at risk for infection with HCV and people with signs or symptoms of hepatitis... Molecular Signatures May Aid Fight Against Pediatric Liver Disease Researchers have identified a set of "molecular signatures" for biliary atresia - the most common diagnosis leading to liver transplant in children - that can help identify the progression of disease at diagnosis and predict clinical outcomes... Alnylam Obtains Approvals To Initiate Phase I Study With ALN-TTR01 In Patients With TTR-Mediated Amyloidosis (ATTR) Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), a leading RNAi therapeutics company, announced today that its applications for ALN-TTR01 have been given clearance by Portuguese, Swedish, and British regulatory authorities to begin clinical testing. The trial will begin enrolling patients shortly in a blinded, randomized, placebo-controlled, multicenter Phase I study...

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